Richard D. DiMarchi, Ph.D.
Endocrinology & Drug Development
Dr. DiMarchi is the Linda & Jack Gill Chair in Biomolecular Sciences and
Professor of Chemistry at Indiana University. He is a retired Group Vice
President for Biotechnology and Product Development at Eli Lilly & Company
where for more than two decades he provided leadership in biotechnology,
endocrine research and product development. Professor DiMarchi is recognized
for the discovery and development of rDNA-derived Humalog® (LisPro-human
insulin). This designer insulin represents the first demonstration that
structurally altered rDNA-derived, biosynthetic proteins can improve
pharmacological performance without increasing the risk of an abnormal
immunological response. As scientist and administrator at Lilly, Dr.
DiMarchi participated in the commercial development of Humulin®, Humatrope®,
Xigris®, and Forteo®. The goal of his current research and commercial
endeavors is to develop proteins with enhanced therapeutic properties
through biochemical optimization with non-natural amino acids, an approach
he has termed chemical-biotechnology. Dr. DiMarchi received his Ph.D. from
Indiana University.